Continuous separation of carbohydrates by ion-exchange chromatography

Journal Article · Wed Jan 01 04:00:00 EST 1997 · Separation Science and Technology

DOI:https://doi.org/10.1080/01496399708003187· OSTI ID:471739

Wolfgang, J; Prior, A ^[1]; Bart, H J; Messenboeck, R C ^[2]; Byers, C H ^[3]

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1. Prior Technology, Goetzis (Australia)
2. Univ. Kaiserslautern (Germany)
3. Oak Ridge National Lab., TN (United States)

A synthetic mixture of fructose, mannitol and sorbitol was continuously separated by a chromatographic method using a cation-exchange resin (Dowex 50W-X8) in its Ca{sup 2+}-form as the stationary phase. An annular chromatograph (AC) was used to achieve a continuous mode of operation. Distribution and mass transfer coefficients of the three substances as well as bed properties were obtained by batch chromatography. The separation was simulated mathematically in terms of an approximate linear chromatographic theory was applied to the modeling of the behavior of the continuous separations. The influence of rotation rate, column loading, eluent flow rate and feed concentration on the resolution of the individual peaks were investigated.

• Sponsoring Organization: USDOE
• OSTI ID: 471739
• Report Number(s): CONF-951057--
• Journal Information: Separation Science and Technology, Journal Name: Separation Science and Technology Journal Issue: 1-4 Vol. 32; ISSN 0149-6395; ISSN SSTEDS
• Country of Publication: United States
• Language: English

Related Subjects

40 CHEMISTRY
FRUCTOSE
ION EXCHANGE CHROMATOGRAPHY
MONOSACCHARIDES
SORBITOL