FALL IN THESHOLD TO ELECTRICAL EXCITATION OF X-IRRADIATED ISOLATED FROG NERVE
Journal Article
·
· Intern. J. Radiation Biol.
OSTI ID:4712137
Monophasic action-potentials were recorded in isolated frog sciatic nerves in a humid chamber; constant electric stimuli were given in each experiment at a regular rate of between 12 and 30 stimuli per minute. Preparations were irradiated with 50 kv x rays delivered at a rate of 67 krad/ maximal action-potentials showed an increase of size within 2 sec of commencement of irradiation, and the increase persisted for at least 15 min after the end of the irradiation. The increase was caused by a fall in threshold of the axons in the nerve trunk. However, irradiation did not affect the size of maximal action- potentials, did not produce any gross change of shape in the action-potentials, and did not allow ephaptic transmission between adjacent axons in the nerve trunk. (auth)
- Research Organization:
- Royal Cancer Hospital, London
- NSA Number:
- NSA-17-010417
- OSTI ID:
- 4712137
- Journal Information:
- Intern. J. Radiation Biol., Journal Name: Intern. J. Radiation Biol. Vol. Vol: 5
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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