Novel choline esterase based sensor for monitoring of organophosphorus pollutants
- Univ. of New Mexico, Albuquerque, NM (United States)
Organophosphorus compounds are significant major environmental pollutants due to their intensive use as pesticides. The modern techniques based on inhibition of choline esterase enzyme activity are discussed. Potentiometric electrodes based on detection of choline esterase inhibition by analytes has been developed. The detection of choline esterase activity is based on the novel principle of molecular transduction. Immobilized peroxidase acting as the molecular transducer, catalyzes the electroreduction of hydrogen peroxide by direct (mediatorless) electron transfer. The sensing element consists of a carbon based electrode containing an assembly of co-immobilized enzymes: choline esterase, choline oxidase and peroxidase.
- OSTI ID:
- 469772
- Report Number(s):
- CONF-960804-Vol.1; TRN: 97:002180-0051
- Resource Relation:
- Conference: SPECTRUM `96: international conference on nuclear and hazardous waste management, Seattle, WA (United States), 18-23 Aug 1996; Other Information: PBD: 1996; Related Information: Is Part Of Proceedings of the international topical meeting on nuclear and hazardous waste management (SPECTRUM `96): Volume 1; PB: 885 p.
- Country of Publication:
- United States
- Language:
- English
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