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EFFECT OF THE TREATMENT WITH P-32 ON BLOOD COAGULATION FACTORS IN POLYCYTHEMIA VERA (in Italian)

Journal Article · · Acta Isotopica
OSTI ID:4694243
Blood coagulation factors were investigated in 14 patients with polycythemia vera, before and after P/sup 32/ treatment. In connection with the improvement of clinical signs of thrombosis or hemorrhage and with the red cell count decrease, significant changes were observed, especially in the platelet sector. A general normalization of the platelet function occurred with a decrease from 420000 before to 186200/cmm after the therapy. This was evident with the Heparin tolerance test in vitro: the mean values, which were 6'39"/3 heparin Units/ml, 8'57"/7 heparin U/ml, and 12'31"/10 heparin U/ml before treatment, passed to 7'36", 11'10", and 16'08", in connection with the improvement of the plasmatic thrombogenic diathesis. (P.C.H.)
Research Organization:
Universita, Padua
NSA Number:
NSA-17-021470
OSTI ID:
4694243
Journal Information:
Acta Isotopica, Journal Name: Acta Isotopica Vol. Vol: 1
Country of Publication:
Country unknown/Code not available
Language:
Italian

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