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THE INFLUENCE OF THE TIME DISTRIBUTION OF THE DOSE ON THE BIOLOGICAL EFFECT OF X-RAYS

Thesis/Dissertation ·
OSTI ID:4693438
BS>The influence of the time distribution of the dose on radiation effects after whole-body irradiation of 4000 mice with 100 kvp x rays is studied. LD/sub 50/30/ was taken as index for radiation damage. Values for LD/sub 50/30/ are given for continuous irradiation with 10 different dose rates (1.36 to 139.5 r/min). For dose rates which are larger than 50 r/min, LD/sub 50/ remains constant. For 1.36 r/min, a value of 987 r was observed. Mortalities for fractionated irradiations with constant pulse duration and doses using invervals from 1 to 16 min are given. No dependence of LD/sub 50/ on the sex of mice was observed. Recovery time of damage was determined using the theory of Lea. A dynamic model for the explanation of the results using two dependent recovery processes is proposed. (Gmelin Inst.)
Research Organization:
Originating Research Org. not identified
NSA Number:
NSA-17-030459
OSTI ID:
4693438
Country of Publication:
Country unknown/Code not available
Language:
English