Immediate Retinal Response to X-Rays at Milliroentgen Levels

Journal Article · Fri Feb 01 04:00:00 EST 1963 · Radiation Research

DOI:https://doi.org/10.2307/3571445· OSTI ID:4692150

Bachofer, C. S.; Wittry, S. Esperance

The retina of the grass frog, Rana pipiens, responds immediately to flashes of x rays by producing an electroretinogram. The threshold for this response is approximately 7 mr per flash. Flashes of lower intensity may produce responses, but these are of doubtful validity. A distinction shouid be made between the response to x rays and the damage caused by exposure to x rays. It is possible to expose the retina to hundreds of flashes of x rays with out impairment of the response, provided the interval between flashes is of sufficient duration that the retina may completely recover. Approximately 1 minute is sufficient for complete recovery. When the retina is stimulated at rapid rates, for example, one every 2 seconds, all properties of the electroretinogram, such as amplitude, rate of rise, latent period, and duration, undergo immediate modifications, but on cessation of this rapid stimulation the retina regains its ability to produce an undistorted electroretinogram in approximately 10 minutes even though doses as high as 6000 r have been delivered in this fashion. (auth)

• Research Organization: Univ. of Notre Dame, Ind. and Coll. of St. Catherine, St. Paul
• Sponsoring Organization: USDOE
• NSA Number: NSA-17-023167
• OSTI ID: 4692150
• Journal Information: Radiation Research, Journal Name: Radiation Research Journal Issue: 2 Vol. 18; ISSN 0033-7587
• Publisher: Radiation Research Society
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AMPLITUDE
ANIMALS
BIOLOGY AND MEDICINE
FROGS
NERVOUS SYSTEM
PHYSIOLOGY
QUANTITY RATIO
RADIATION DOSES
RADIATION INJURIES
RADIOSENSITIVITY
RANA
RECOVERY
RETINA
VARIATIONS
VELOCITY
X RADIATION