The Generation Cycle of Duodenal Crypt Cells of Mice Exposed to 220 Roentgens of Cobalt-60 Gamma Irradiation per Day

Journal Article · Thu Aug 01 04:00:00 EDT 1963 · Radiation Research

DOI:https://doi.org/10.2307/3571483· OSTI ID:4683605

Fry, R. J. M.; Lesher, S.; Sallese, A.; Staffeldt, E.

The mucosal epithelium of the duodenum of BCF₁ mice exposed to 220 r/day for 1, 7, 14, 17, and 18 days was studied and compared to that of nonirradiated controls of same age. The generation time of the duodenal crypt cells of mice irradiated for 1, 7, and 14 days, and of the controls, was determined. Since it was found that cells are cold up between the end of synthesis and the completion of tosis, the initial effect may be similar to the effect produced by a single exposure. When exposure is continued. The there is an attempt to compensate for cell loss by a speeding up of the generation cycle which is primarily due to a

• Research Organization: Trinity Coll., Dublin; Argonne National Lab., Ill.
• Sponsoring Organization: USDOE
• NSA Number: NSA-17-033735
• OSTI ID: 4683605
• Report Number(s): TID-17602; UAC-6973
• Journal Information: Radiation Research, Journal Name: Radiation Research Journal Issue: 4 Vol. 19; ISSN 0033-7587
• Publisher: Radiation Research Society
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ANIMAL CELLS
BIOLOGY AND MEDICINE
COBALT 60
CONTROL
DOSE FRACTIONATION
DUODENUM
GAMMA RADIATION
INTESTINE
MICE
MITOSIS
RADIATION DOSES
RADIATION EFFECTS