EVIDENCE FOR INDIRECT EFFECTS OF RADIATIONS OF HEAVY IONS AND ELECTRONS ON HAIR DEPIGMENTATION

Journal Article · Fri Feb 15 04:00:00 EST 1963 · Annals of the New York Academy of Sciences (U.S.)

OSTI ID:4674764

Chase, H B; Straile, W E; Arsenault, C

Localized irradiations of hair follicles of mice, made possible by short- range heavy ions from a heavy ion linear accelerator and by collimated narrow slft beams of accelerated electrons, demonstrafe depigmentation effects remote from the site of original irradiation damage and also depigmentation effects delayed until the second hair growth following irradiation. To explain these indirect effects, the tentative hypothesis is again proposed that suggests that the upper permanent external sheath is the true germ. It produces the new lower external sheath and bulb of each hair generation, and damage from irradiation causes it to fail in fts capacity of incorporating and culturing the potential melanocytes which are present primarily in the dermal papilla or the resting epithelial tab conventionally called the germ. In any case, with respect to pigmentation and melanocytes, there are indirect effects of irradiation. (auth)

• Research Organization: Brown Univ., Providence
• NSA Number: NSA-17-031882
• OSTI ID: 4674764
• Journal Information: Annals of the New York Academy of Sciences (U.S.), Journal Name: Annals of the New York Academy of Sciences (U.S.) Vol. Vol: 100; ISSN ANYAA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ANIMAL CELLS
BIOLOGY AND MEDICINE
CYTOLOGY
DISTRIBUTION
ELECTRON BEAMS
HAIR
IONS
LINEAR ACCELERATORS
MELANOCYTES
MICE
PIGMENTS
RADIATION EFFECTS
SKIN