Assignment of human KH-box-containing genes by in situ hybridization: HNRNPK maps to 9q21.32-q21.33, PCBP1 to 2p12-p13, and PCBP2 to 12q13.12-q13.13, distal to FRA12A

Journal Article · Fri Mar 01 04:00:00 EST 1996 · Genomics

DOI:https://doi.org/10.1006/geno.1996.0121· OSTI ID:466608

Tommerup, N ^[1]; Leffers, H ^[2]

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1. John F. Kennedy Inst., Glostrup (Denmark)
2. Univ. Hospital, Copenhagen (Denmark)

This report describes the localization of various human KH-box-containing genes using fluorescence in situ hybridization. Accordingly, HNRNPK was mapped to human chromosome 9q21.32-q21.33, PCBP1 was mapped to human chromosome 2p12-p13, and PCBP2 was mapped to human chromosome 12q13.12-q13.13. These proteins affect RNA-binding capability. 13 refs., 1 fig.

• OSTI ID: 466608
• Journal Information: Genomics, Journal Name: Genomics Journal Issue: 2 Vol. 32; ISSN GNMCEP; ISSN 0888-7543
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
AMINO ACID SEQUENCE
CHROMOSOMAL ABERRATIONS
DNA HYBRIDIZATION
DNA SEQUENCING
DNA-CLONING
FLUORESCENCE
FOLIC ACID
GENE MUTATIONS
GENES
GENETIC MAPPING
HEREDITARY DISEASES
HUMAN CHROMOSOME 12
HUMAN CHROMOSOME 2
HUMAN CHROMOSOME 9
HUMAN X CHROMOSOME
MAN
MENTAL DISORDERS
NUCLEOTIDES
PROTEINS
SPLICING
STRUCTURE-ACTIVITY RELATIONSHIPS