CANCER THERAPY--EVALUATION OF SUPERVOLTAGE X RAY
Journal Article
·
· California Medicine (U.S.) Changed to West. J. Med.
OSTI ID:4663592
Criticisms are advanced of the statistical treatment of previous studies purporting to show that supervoltage xray therapy is not more effective than orthovoltage therapy in treatment of cancer of tonsil and ovary. The formula used previously for chi-square was found to be in error. It should be multiplied by one less than the number of studies (16 for tonsil, 11 for ovary). This, plus the correction of minor arithmetic errors, leads to chi-squares of 69.97 (significant) for tonsil and 24.75 (significant at the 1% level) for ovary. It is suggested that further examination of the data should logically consist in deciding whether the observed variation is associated to any significant extent with variation in voltage. This can be done by calculating separate chi-squares for the variation within the high-voltage group, within the other group (ortho- voltagenot stated), and between the high-voltage and the other group. Since these represent all possible sources of variation, the chi squares add up to the overall chi square calculated above. For both organs, the significant variation occurs within the other group, not within the high-voltage group or between the 2 groups. Therefore the failure to find such a difference in the data is not a reason to conclude that none exists. Thus it was concluded that the previously presented data do not prove the equality of the 2 treatments. (TCO)
- Research Organization:
- Dept. of Public Health, Sacramento, Calif.
- NSA Number:
- NSA-17-026973
- OSTI ID:
- 4663592
- Journal Information:
- California Medicine (U.S.) Changed to West. J. Med., Journal Name: California Medicine (U.S.) Changed to West. J. Med. Vol. Vol: 7; ISSN CAMEA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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