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U.S. Department of Energy
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THE IN VIVO INCORPORATION OF TRITIATED CYTIDINE AND TRITIATED THYMIDINE BY THE CESTODE, HYMENOLEPIS MICROSTOMA

Technical Report ·
OSTI ID:4647310

The mouse bile duct cestode, Hymenolepis microstoma, was exposed in vivo in separate experiments to tiitiated cytidine and tritiated thymidine, respectively. Nucleolar and nuclear labeling, by cytidine, and nuclear labeling, by thymidine, as revealed by autoradiographic methods, occurred in both host and cestode tissues. As expected, only mitotically or synthetically active nuclei were labeled, those of the neck, developing organs, and embryos of the cestode. Bile-duct epithelium and pancreatic acinar cells, autoradiographed as a control, showed the same degree and localization of cytidine labeling as the active cells of the cestode. The assimilation of cytidine amd thymidine by direct absorption from the fluid contents of the bile duct implies that cestodes can absorb such materials from their immediate environment. (auth)

Research Organization:
Tennessee. Univ., Knoxville
NSA Number:
NSA-17-040490
OSTI ID:
4647310
Report Number(s):
TID-18025
Country of Publication:
United States
Language:
English