Uptake of fluorine-18-fluorodeoxyglucose in sarcoidosis

Journal Article · Sat Oct 01 04:00:00 EDT 1994 · Journal of Nuclear Medicine

OSTI ID:458860

Lewis, P J; Salama, A ^[1]

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1. Guy`s Hospital, London (United Kingdom)

Whole-body PET scanning was performed using {sup 18}F-fluorodeoxyglucose (FDG) in two patients with hilar lymphadenopathy in whom the clinical differential diagnosis was between sarcoidosis and lymphoma. Both patients were later proven to have sarcoidosis. Uptake of {sup 18}FDG was seen in both intra- and extrathoracic lesions as well as in associated erythema nodosum. One patient underwent a repeat scan after steroid therapy where a marked decrease in hilar uptake was seen. Fluorine-18-fluorodeoxyglucose uptake is observed in lymph nodes with sarcoid involvement. Further investigation is necessary to assess if quantitative differences exist between sarcoid and malignant lymphadenopathy. 30 refs., 3 figs.

• OSTI ID: 458860
• Journal Information: Journal of Nuclear Medicine, Journal Name: Journal of Nuclear Medicine Journal Issue: 10 Vol. 35; ISSN JNMEAQ; ISSN 0161-5505
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
ERYTHEMA
FLUORINE 18
FLUORODEOXYGLUCOSE
LYMPH NODES
PATIENTS
POSITRON COMPUTED TOMOGRAPHY
UPTAKE