Asymmetric hydrogenation of ethyl pyruvate: Diffusion effects on enantioselectivity

Journal Article · Mon Jul 01 00:00:00 EDT 1996 · Journal of Catalysis

DOI:https://doi.org/10.1006/jcat.1996.0238· OSTI ID:447120

Sun, Yongkui; Wang, Jian; LeBlond, C ^[1]

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1. Merck & Co., Inc., Rahway, NJ (United States); and others

Enantioselectivity in the hydrogenation of ethyl pyruvate over cinchona-alkaloid-modified Pt has been studied. Kinetic studies indicated different mechanisms in different reaction regimes. Solution hydrogen concentration strongly corrrelated with reaction rates and enantioselectivity. 28 refs., 5 figs., 2 tabs.

• OSTI ID: 447120
• Journal Information: Journal of Catalysis, Journal Name: Journal of Catalysis Journal Issue: 2 Vol. 161; ISSN 0021-9517; ISSN JCTLA5
• Country of Publication: United States
• Language: English

Related Subjects

10 SYNTHETIC FUELS
40 CHEMISTRY
CATALYSTS
CATALYTIC EFFECTS
CHEMICAL REACTION KINETICS
ESTERS
HYDROGENATION
PLATINUM
STEREOCHEMISTRY