Lymphocyte response after radiotherapy
Journal Article
·
· Lancet, no. 7830, p. 683
The lymphocyte response of 48 patients with carcinoma of the bronehus was studied before and after radical radiotherapy using phytohendagglutinin (P.H. A.) and pokeweed mitogen (P. W. M.). The absolute lymphocyte-count bcfore and after treatment was also assessed. The patients received an average dose of 3200 rad in eight fractions, given twice weekly over 4 weeks. The average fall in the absolute lymphocyte-count was 50% of the original number. The average proportional drop in the P.H.A. response of the lymphocytes was 45%. The average response of the lymphocytes to P.W.M. was not affected by the treatment. It is suggested that thesc results indicate that it is the T (thymus-dependent) population of lymphocytes that is affected by treatment with radiotherapy and the R population remains unchanged. (auth)
- Research Organization:
- Velindre Hospital, Whitchurch, Wales
- NSA Number:
- NSA-29-000637
- OSTI ID:
- 4423225
- Journal Information:
- Lancet, no. 7830, p. 683, Journal Name: Lancet, no. 7830, p. 683; ISSN LANCA
- Country of Publication:
- United Kingdom
- Language:
- English
Similar Records
Longitudinal studies of blood lymphocyte capacity in Hodgkin's disease
B and T lymphocytes in man. I. Effect of infant thymic irradiation on the circulating B and T lymphocytes
Impaired B lymphocyte reactivity in patients after radiotherapy
Journal Article
·
Sat Oct 31 23:00:00 EST 1981
· Cancer (Philadelphia); (United States)
·
OSTI ID:5388713
B and T lymphocytes in man. I. Effect of infant thymic irradiation on the circulating B and T lymphocytes
Conference
·
Wed Dec 31 23:00:00 EST 1975
·
OSTI ID:4053576
Impaired B lymphocyte reactivity in patients after radiotherapy
Journal Article
·
Sun Mar 31 23:00:00 EST 1985
· Int. J. Radiat. Oncol., Biol. Phys.; (United States)
·
OSTI ID:5566414