Disaggregation of polysomes in rat thymus following whole-body x irradiation

Journal Article · Wed Dec 01 04:00:00 EST 1971 · Indian J. Biochem. Biophys., v. 8, no. 4, pp. 254-256

OSTI ID:4422552

Saroja, S; Patil, M S; Sreenivasan, A

Polysomal profiles of the rat thymus examined at 18 and 48 hr following whole-body exposure to x rays (600 R) exhibited shifts from heavier aggregates towards monosomes. These changes were accompanied by significant increase in alkaline ribonuclease (RNase) activity with concomitant decrease in alkaline RNase inhibitor levels. The results suggest that disaggregation of polysomes after irradiation may be the consequence of activation of alkaline RNase resulting from the fall in the levels of the inhibitor. (auth)

• Research Organization: Bhabha Atomic Research Centre, Bombay
• NSA Number: NSA-29-000718
• OSTI ID: 4422552
• Journal Information: Indian J. Biochem. Biophys., v. 8, no. 4, pp. 254-256, Journal Name: Indian J. Biochem. Biophys., v. 8, no. 4, pp. 254-256; ISSN IJBBB
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

*RIBOSOMES-- BIOLOGICAL RADIATION EFFECTS
N48520* --Life Sciences--Radiation Effects on Animals-- Vertebrates
PHOTON BEAMS
RATS
RNA- ASE
THYMUS
WHOLE-BODY IRRADIATION
X RADIATION