Studies on the circulation of the femoral head using catheter semiconductor radiation detector

Journal Article · Sun Jul 01 04:00:00 EDT 1973 · Nippon Seikei Geka Gakkai Zasshi, v. 47, no. 7, pp. 581-617

OSTI ID:4391348

Hayashi, M

The radioisotope used in those studies was /sup 32/P- deisopropylfluorophosphate (DF/sub 3/P) which is a blood-seeking pure beta emitter. In order to detect the radioactivity in the femoral head in vivo, a catheter semiconductor radiation detector with a sufficiently small size and sensitivity to beta radiation was inserted into the femoral head. The counting rates recorded at the femoral heads of human normal controls increased rapidly for the first few minutes, and a plateau was reached in five minutes or so. The counting rates recorded at each portion of normal control were almost constact. The head-to-trochanter ratios were approximately 1.0 in four cases. In the six hips of the five patients with idiopathic avascular necrosis, the head-to trochanter ratios of counts per minutes were correlated to pathological change in the portions, i.e., the ratios of 0.15 to 0 were obtained in the portions with roenigenographical density and pathological necrosis or sclerosis, while 0.56 to 1.20 were obtained in the radiolucent and vascular-fibrous portions. In the six hips of the six patients with fracture of the femoral neck (non-union), the head- totrochanter ratios of 0.26 to 0 were correlated with pathological changes such as bone necrosis, sclerosis, and marrow fibrosis. In the sixteen hips of the fifteen patients with osteoarthnitis, the head-to-trochanter ratios 1.02 to 0.08 were correlated to degenerative process of the disease, suggesting the decrease of arterial blood flow along with the aggravation of the process. It was concluded that this method is useful in estimating the arterial blood flow in the femoral head with a decrease or partial or total increase and hence for diagaosis and prognosis. (auth)

• Research Organization: Chiba Univ., Japan
• NSA Number: NSA-29-010506
• OSTI ID: 4391348
• Journal Information: Nippon Seikei Geka Gakkai Zasshi, v. 47, no. 7, pp. 581-617, Journal Name: Nippon Seikei Geka Gakkai Zasshi, v. 47, no. 7, pp. 581-617; ISSN NSGZA
• Country of Publication: Japan
• Language: Japanese

Related Subjects

*BLOOD FLOW-- TRACER TECHNIQUES
*BONE JOINTS-- BLOOD CIRCULATION
BONE FRACTURES
BONE MARROW
DIAGNOSTIC TECHNIQUES
INFECTIOUS DISEASES
N48830* --Life Sciences--New Tracer Techniques--Other
PATIENTS
PHOSPHORUS 32
SENSITIVITY
SI SEMICONDUCTOR DETECTORS
X RADIATION