Studies on the effects of gamma radiation on 6-aminopenicillanic acid and its derivatives by the EPR method

Journal Article · Mon Jan 01 00:00:00 EST 1973 · Bull. Acad. Pol. Sci., Ser. Sci. Chim., v. 21, no. 7-8, pp. 605-609

OSTI ID:4375446

Dziegielewski, J; Jezowska-Trzebiatowska, B; Kozlowski, H

Commercial samples of 6-aminopenicillanic acid (6-APA), potassium benzyl- penicillin; procaine benzyl-penicillin, procaine hydrochlorides and sodium 3-(o- chlorophenyl)-5-methyl-4-isoxasol penicillin salt were irradiated with 0.5 to 40 Mrad and examined by the EPR method within the temperature range 100 to 300 deg K. No influence of the irradiation dose on powder EPR spectra structure has been stated, except for benzyl-penicillin procaine. In irradiated samples of antibiotics the presence of radicals with unpaired electrons on sulfur atoms and carbon atoms abuttmg on the thioether group has been stated. (auth)

• Research Organization: Univ., Warsaw
• NSA Number: NSA-29-012583
• OSTI ID: 4375446
• Journal Information: Bull. Acad. Pol. Sci., Ser. Sci. Chim., v. 21, no. 7-8, pp. 605-609, Other Information: Orig. Receipt Date: 30-JUN-74
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

N40300* -Chemistry-Radiation Chemistry
*ANTIBIOTICS- RADIOLYSIS
ELECTRON SPIN RESONANCE
GAMMA RADIATION
LOW TEMPERATURE
MEDIUM TEMPERATURE
RADIATION CHEMISTRY
RADICALS