Separation of tin-113 and indium-113m by thin-layer chromatography

Journal Article · Sun Jul 01 04:00:00 EDT 1973 · Jap. Anal., v. 22, no. 7, pp. 856-860

OSTI ID:4368527

Maki, Y

The separation of /sup 113m/In from a mixture of /sup 113/Sn-/sup 113m/ In in a radioactive equilibrium was carried out by a thin-layer chromatographic method using silica gel as the adsorbent and dilute acetic acid as the developer. At first, the separation of nonradioactive Sn(II), Sn(IV), and In(III) ions were tested by using various concentrations of acetic acid solutions. By increasing the concentration of acetic acid, a higher R/sub f/ value for In(III) was obtained. On the contrary, Sn(IV) was retained at the original point and Sn(II) advanced with tailing because it was oxidized to Sn(IV) during the development. Accordingly, in order to let Sn stay at the origin, Sn(II) must be oxidized to Sn(IV) by adding H/sub 2/0/sub 2/ into the sample solution before the development. The best separation of Sn and In was obtained by the solvent consisting of acetic acid: water (1: 10), by which the R/sub f/ values were 0.00 for Sn(IV) and 0.90 for In(III). The spread of Sn(IV) spot was investigated by using sample solutions at various HCl conceritration. Sn(IV) spread with increasing the HCl concentration, while In(III) spot stayed at the position of R/sub f/ value 0.90 irrespective of the HCl concentration. Accordingly, in order to obtain a clear separation of the spots of these two ions, the HCl concentration of the sample solution must be adjusted at about 1N. The development could be achieved within about 20 min by raising the developing solvent 5 cm high from the original point. Iridium-113m was separated from /sup 113/Sn by applying the method mentioned above. The radiochemical purity of the /sup 113m/In scratched from the developed plate was identified to be more than 99.8%. By analyzing its decay curve, about 93% of it was extracted from the adsorbent by 5 ml of an acetic acid: water mixture (1 ; 10). (auth)

• Research Organization: Industrial Research Inst. of Kanagawa Prefecture, Yokohama, Japan
• NSA Number: NSA-29-007643
• OSTI ID: 4368527
• Journal Information: Jap. Anal., v. 22, no. 7, pp. 856-860, Journal Name: Jap. Anal., v. 22, no. 7, pp. 856-860; ISSN BNSKA
• Country of Publication: Japan
• Language: Japanese

Related Subjects

*INDIUM 113-- THIN-LAYER CHROMATOGRAPHY
*TIN 113-- THIN-LAYER CHROMATOGRAPHY
ACETIC ACID
CHEMICAL REACTION YIELD
DEVELOPERS
HYDROCHLORIC ACID
HYDROGEN PEROXIDE
ISOMERIC NUCLEI
N40440* --Chemistry--Radiochemistry & Nuclear Chemistry-- Radioisotope Production
QUANTITY RATIO
SEPARATION PROCESSES
SILICA GEL
WATER