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Analysis of $sup 131$I-thyroxine bound protein by the adverse Partigen method (in Japanese)

Journal Article · · Igaku No Ayumi, v. 84, no. 5, pp. 261-262
OSTI ID:4360905
2O mu Ci of /sup 131/I-thyroxine (T/sub 4/) was added to the serum samples (0.1 to 0.2 ml) obtained from 1 normal adult, 2 patients with thyroxine- binding globulin (TBG) defect, and 1 patient with decreasing TBG. The samples were dissolved in agarose solution and were dried, to which anti-sera were added. The prepared samples were examined by autoradiography and with protein-dye method. The significant radioactivity was observed in prealbumin, BETA -lipoprotein, and hemopexin in the serum sample of normal adult. This finding is suggested that limopexin is one of the thyroxine binding protein (TBP), for it is binding with / sup 131/I-T/sub 4/. The radioactivity was slight in albumin and alpha /sub 1/- lipoprotein. No significant defference was observed between serum samples of normal adult and of TBG defective patient. (JA)
Research Organization:
Kumamoto Univ., Japan
NSA Number:
NSA-29-010554
OSTI ID:
4360905
Journal Information:
Igaku No Ayumi, v. 84, no. 5, pp. 261-262, Journal Name: Igaku No Ayumi, v. 84, no. 5, pp. 261-262; ISSN IGAYA
Country of Publication:
Japan
Language:
Japanese

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