Vibrational spectra and structure of some penicillin derivatives. Part III. Amphicillin and carboxybenzylpenicillin

Journal Article · Mon Jan 01 04:00:00 EST 1973 · Bull. Acad. Pol. Sci., Ser. Sci. Chim., v. 21, no. 9, pp. 657-668

OSTI ID:4344655

Dziegielewski, J; Hanuza, J; Jezowska-Trzebiatowska, B; Kuduk- Jaworska, J

IR spectra of sodium salts and acids of amphicillin and carboxybenzlpenicillin were investigated in the solid state over the 100-200 cm/ sup -1/ region. Interpretation of the spectra and band assignments was made on the basis of both frequency shifts caused by deuteration and the information on penicillin-like antibiotics from previous studies. The molecular configuration of such a type of antibiotics was suggested, based on the position of characteristic amide and carbonyl bands. Lactam-thiazolidine skeleton vibrations are identified and located. The information obtained will be used in studies on ir spectra of the gamma radiolysis products resulting from lactam-thiazolidine antibiotics to define the radiolysis products and the mechanism of decomposition. (auth)

• Research Organization: Joliot-Curie Univ., Warsaw
• NSA Number: NSA-29-015354
• OSTI ID: 4344655
• Journal Information: Bull. Acad. Pol. Sci., Ser. Sci. Chim., v. 21, no. 9, pp. 657-668, Journal Name: Bull. Acad. Pol. Sci., Ser. Sci. Chim., v. 21, no. 9, pp. 657-668; ISSN BAPCA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

*ANTIBIOTICS-- RADIOLYSIS
*DEUTERIUM-- ISOTOPE EFFECTS
CHEMICAL REACTION KINETICS
DEUTERIUM COMPOUNDS
GAMMA RADIATION
INFRARED SPECTRA
N40220* --Chemistry--Inorganic
Organic
& Physical Chemistry--Isotopic Effects
N40300 --Chemistry--Radiation Chemistry
STRUCTURAL CHEMICAL ANALYSIS