Thermal and radiolytic decomposition of $sup 131$I-19-iodocholesterol
Journal Article
·
· J. Nucl. Med., v. 15, no. 1, pp. 38-41
OSTI ID:4330369
Using accelerated decomposition studies, the thermal and radiolytic decomposition of /sup 131/I-19-iodocholesterol was determined. Thermal decomposition was the major cause of decomposition of /sup 131/I-19- iodocholesterol in its present formulation. Radiation decomposition does not significantly affect radiochemical purity over the expiration time of the product. A G value of 2.56 and an energy of activation of 34.6 kcal/mole were obtained with /sup 131/I-19-iodocholesterol. Radiochemical purity of 70% was obtained in 16 days if stored at 5 deg C and 3 days if stored at room temperature. (auth)
- Research Organization:
- Univ. of Michigan, Ann Arbor
- NSA Number:
- NSA-29-020720
- OSTI ID:
- 4330369
- Journal Information:
- J. Nucl. Med., v. 15, no. 1, pp. 38-41, Journal Name: J. Nucl. Med., v. 15, no. 1, pp. 38-41; ISSN JNMEA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
Similar Records
Chemical and radiochemical stability of the adrenal-scanning agents, 6beta-iodomethyl-19-norcholest-5(10-en-3beta-ol and 19-iodocholest-5-en-3beta-ol)
Percent uptake of $sup 131$I radioactivity in some organs from $sup 131$I- 19-iodocholesterol as adrenal tumor localizing agent
Concentration of radiolabeled cholesterol in a feminizing adenoma of the testis. [19-(/sup 131/I)-iodocholesterol]
Journal Article
·
Sat Oct 01 00:00:00 EDT 1977
· Steroids; (United States)
·
OSTI ID:5658203
Percent uptake of $sup 131$I radioactivity in some organs from $sup 131$I- 19-iodocholesterol as adrenal tumor localizing agent
Journal Article
·
Mon Oct 01 00:00:00 EDT 1973
· Nippon Naibumpi Gakkai Zasshi, v. 49, no. 10, pp. 1245-1253
·
OSTI ID:4327996
Concentration of radiolabeled cholesterol in a feminizing adenoma of the testis. [19-(/sup 131/I)-iodocholesterol]
Journal Article
·
Sat Mar 31 23:00:00 EST 1979
· J. Nucl. Med.; (United States)
·
OSTI ID:6295656
Related Subjects
*CHOLESTEROL-- AUTORADIOLYSIS
*ORGANIC IODINE COMPOUNDS-- AUTORADIOLYSIS
DECOMPOSITION
IMPURITIES
IODINE 131
LABELLED COMPOUNDS
N40300* --Chemistry--Radiation Chemistry
N40420 --Chemistry--Radiochemistry & Nuclear Chemistry--Properties of Radioactive Materials
N48830 --Life Sciences--New Tracer Techniques--Other
NUCLEAR MEDICINE
RADIOPHARMACEUTICALS
STORAGE
TEMPERATURE DEPENDENCE
*ORGANIC IODINE COMPOUNDS-- AUTORADIOLYSIS
DECOMPOSITION
IMPURITIES
IODINE 131
LABELLED COMPOUNDS
N40300* --Chemistry--Radiation Chemistry
N40420 --Chemistry--Radiochemistry & Nuclear Chemistry--Properties of Radioactive Materials
N48830 --Life Sciences--New Tracer Techniques--Other
NUCLEAR MEDICINE
RADIOPHARMACEUTICALS
STORAGE
TEMPERATURE DEPENDENCE