Comparison of frequencies of radiation-induced stable chromosomal aberrations in somatic and germ tissues of the mouse

Journal Article · Sat Dec 01 04:00:00 EST 1973 · Mutat. Res., v. 20, no. 3, pp. 369-376

DOI:https://doi.org/10.1016/0027-5107(73)90058-4· OSTI ID:4328117

van Buul, P P.W.

Radioinduced stable chromosome aberrations have been studied in the testes and bone-marrow of the mouse (Mus musculus). Sixty days after whole-body irradiation with a dose of 400 rad x-rays, the frequency of visible chromosome aberrations in bone-marrow cells was 19.8%. The frequency of chromosome aberrations in spermatogonia of the same mice, scored as multivalents in spermstocytes, was considerably lower, only 4.7%. The possible mechanisms underlyin this marked difference in translocation yield are discussed. (auth)

• Research Organization: Univ., Lieden
• Sponsoring Organization: USDOE
• NSA Number: NSA-29-021193
• OSTI ID: 4328117
• Journal Information: Mutat. Res., v. 20, no. 3, pp. 369-376, Journal Name: Mutat. Res., v. 20, no. 3, pp. 369-376; ISSN MUREA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

*BONE MARROW CELLS-- CHROMOSOMAL ABERRATIONS
*BONE MARROW-- BIOLOGICAL RADIATION EFFECTS
*CHROMOSOMAL ABERRATIONS-- RADIOINDUCTION
*SPERMATOGONIA-- CHROMOSOMAL ABERRATIONS
*TESTES-- BIOLOGICAL RADIATION EFFECTS
MICE
N48520* --Life Sciences--Radiation Effects on Animals-- Vertebrates
PHOTON BEAMS
TISSUES
X RADIATION