METABOLISM OF Sr$sup 90$ IN ADULT BEAGLE DOGS
Retent~on and plasma concentrat~on of Srgs tn young Retention and plasma concentration of Sr/sup 90/ in young adult beagle dogs has been determined for 2 year following a single intravenous injection. Retention (% (Editor, I had to insert the three above lines because they came in with letters all over the place) adult beagle dogs has been determtned for 2 years followtng a s~ngle mntravenous tnject~on. Retent~on (% dose) follows the power function (t in days) R = 70.9 t/sup-0.198/. Comparison of these results with those from similar studies with Ra/sup 226/ shows the anticipated similarity in metabolism of Sr/sup 90/ and Ra/sup 226/. However, there are real differences. Sr/sup 90/ retention is less than that of Ra/sup 226/ even though Ra/sup 226/ is excreted more efficiently. This results from higher Sr/sup 90/ plasma concentration. Since Sr/ sup 90/ deposits mainly in the skeleton and its daughter Y/sup 90/ does not translocate, this retention equation can be used to calculate average skeleta1 dose rates for these dogs. (auth)
- Research Organization:
- Univ. of Utah, Salt Lake City
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-13-001080
- OSTI ID:
- 4286830
- Journal Information:
- Proc. Soc. Exptl. Biol. Med., Journal Name: Proc. Soc. Exptl. Biol. Med. Vol. Vol: 99
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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Related Subjects
AGE
BIOCHEMISTRY
BIOLOGY AND MEDICINE
BLOOD PLASMA
BLOOD VESSELS
BONES
CARBON
CARBON 14
CARBON DIOXIDE
CARBOXYLIC ACIDS
CHROMATOGRAPHY
DISTRIBUTION
LABELLED COMPOUNDS
MATHEMATICS
METABOLISM
ORGANIC ACIDS
PHOSPHATES
PHOTOSYNTHESIS
QUANTITY RATIO
RADIOAUTOGRAPHY
RADIUM 226
RETENTION
SKELETON
STRONTIUM 90
TRACER TECHNIQUES
URINE
YTTRIUM 90