The Radiochemical Degradation of a Number of Amino Acids; RADIATSIONNO-KHIMICHESKII RASPAD VODNYKH RACTVOROV NEKOTORYKH AMINOKISLOT
The radiochemical degradation of DL-methionine, DL-valine, DL- alpha - aminobutyric acid, and DL-lysine was studied. Aqueous solutions of these amino acids were irradiated by different doses of x and gamma rays. With rays was investigated as well. The radiochemical degradation of derivatives of DL- methionine, methioninesulfoxide, methioninesulfone, and methionine sulfoximine, was studied simultaneously. The amount of ammonia and of a number of degradation products as well as the decrease of the original amino acid was determined as a function of the irradiation dose. In the studies of the compounds from the degradation, the main interest was centered on the ninhydrin positive substances. These products were studied by paper chromatography and electrophoresis. The identity of some compounds was determined by isolation and infrared spectrography. After irradiation of a solution of DL-valine there were found 12 ninhydrinpositive compounds. Alanine, alpha -aminobutyric acid, aspartic acid, glutamic acid, and threonine were identified. These substances were found in the solution of irradiated alpha aminobutyric acid as well. The solution of irradiated DL-methionine contained, besides the substances described elsewhere, these compounds: 5 ninhydrinpositive substances identified as alanine, threonine, serine, aspartic acid, and alpha -aminobutyric acid; and 22 products of acidic character containing sulfur. An analogy in the effects of x, gamma , and BETA irradiation was found. (auth)
- Research Organization:
- Czechoslovakia
- NSA Number:
- NSA-13-006490
- OSTI ID:
- 4285915
- Report Number(s):
- A/CONF.15/P/2117
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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