Effect of high energy protons on the spinal cord
The spinal cord in the rabbit was irradiated with a 185-Mev proton beam from a 230 cm synchrocyclotron. Using a 1.5 mm broad beam, it was possible to effect sharply delimlted lesions of the spinal cord with only minimal hemorrhages and without any general reactions. With a 10 mm beam the tissue reactions are much more severe. The histopathology of the acute radiation necrosis is described and the factors responsible for its appearance are discussed, especially the width of the proton beam and the size of the single radiation dose.
- Research Organization:
- Univ. of Uppsala
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-13-008551
- OSTI ID:
- 4272872
- Journal Information:
- Acta Radiologica, Journal Name: Acta Radiologica Journal Issue: 1 Vol. 51; ISSN 0001-6926
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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