DAILY VARIATIONS IN THE THYROIDAL UPTAKE OF I$sup 131$ IN HUMAN SUBJECTS

Journal Article · Mon Jun 01 04:00:00 EDT 1959 · J. Clin. Endocrinol. and Metabolism

DOI:https://doi.org/10.1210/jcem-19-6-632· OSTI ID:4267659

Levy, R P; Caughey, P; Turell, D

Forty-nine euthyroid subjects were studied on two successive days to evaluate the constancy of thyroidal I/sup 131/ uptake. The thyroidal uptake of I/ sup 131/ and the urinary excretion of iodide (I/sup 127/) were measured three and twenty-four hours after giving I/sup 131/ tracers. Six patients had day-to-day changes in 24-hour I/sup 131/ uptake of more than 10 per cent of the administered tracer; 3 had variations of 3-hour I/sup 131/ uptake of more than 6 per cent. No correlation between the variability of the thyroidal uptake of I/sup 131/ and the amount of iodide excreted was found when the daily excretion was less than 500 ic g; when more than this amount was excreted, variability in thyroidal I/sup 131/ uptake from one day to the next was no longer encountered. Thus, when an apparent discrepancy between the clinical picture and the thyroidal uptake of I/sup 131/ is observed, day-to-day variation of this index of thyroid function should be considered among the possible causes of such a finding. ( auth)

• Research Organization: Western Reserve Univ.; University Hospitals; Veterans Administration Hospital, Cleveland
• Sponsoring Organization: USDOE
• NSA Number: NSA-13-013181
• OSTI ID: 4267659
• Journal Information: J. Clin. Endocrinol. and Metabolism, Journal Name: J. Clin. Endocrinol. and Metabolism Vol. Vol: 19
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
IODIDES
IODINE 127
IODINE 131
LABELLED COMPOUNDS
MAN
MEASURED VALUES
MEDICINE
METABOLISM
PHYSIOLOGY
QUANTITY RATIO
THYROID
TRACER TECHNIQUES
URINE
VARIATIONS