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U.S. Department of Energy
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Cytogenetic Effect of Ionizing Irradiation on the Spermatogenesis in Monkeys; TSITOGENETICHESKII EFFEKT VOZDEISTVIYA IONIZIRUYUSHCHEGO IZLUCHENIYA NA YADRA ZARODYSHEVYKH KLETOK OBYAZ'YAN

Technical Report ·
OSTI ID:4265254
Exposure to total-body irradiation with 150 to 450 r resulted in considerable nuclear distrubances at various stages of spermatogenesis. Among the observed disturbances were: pycnosis and degeneration of nuclei, adhesion of chromosomes, nuclear decay into karyosomes and lumps, formations of double or quadruple nuclear cells, disturbances in the fusiform apparatus, anaphase bridges, and acentric fragments. A single exposure to 150 to 450 r produced injurious effects on the sexual gland cells which lasted for 2 years and probably will continue during the rest of life. Experimental data on the effects of radiation on the hereditary structures in apes and mice showed a much stronger radiosensitivity in apes. The conception of cell destruction as the result of unbalanced nuclei, following a long period after irradiation, which leads to the exclusion of cytogenic effects of irradiation was proved to be erroneous. (R.V.J.)
Research Organization:
U.S.S.R.
NSA Number:
NSA-13-006326
OSTI ID:
4265254
Report Number(s):
A/CONF.15/P/2476
Country of Publication:
Country unknown/Code not available
Language:
English