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DEPOSITION AND REMOVAL OF RADIOISOTOPES FROM THE BODY. Quarterly Progress Report for October 1, 1958-December 31, 1958

Technical Report ·
OSTI ID:4255446
; ;
Work has continued on the reasons for the ability of certain sugars and sugar derivatives to increase gastrointestinal absorption of strontium and calcium. This property appears to be related, at least in parts to increased fluid retention in the gastrointestinal tract. Since versene has been found to suppress the action of lactose it is concluded that the sugars act only on ionized or readily ionizable strontium or calcium. The action of lactose is observed even when it is administered 2 hours after the alkaline earth. Chemical studies have indicated that the carbohydrates most probably do not act by modification of the solubility of alkaline earth salts. Studies have been started to determine the practicality of reducing retention of acute dosages of radiostrontium by administration of levels of stable strontium high enough to reduce calcification rate as well as provide some measure of isotope dilution. Experiments have been designed and initial studies carried out with rats that may lead to an understanding of the absorptive processes that are operative for calcium and strontium. These are based on development of animals that have specific alkaline earth absorption patterns because of previous nutritional historys and the subsequent testing of these patterns by use of graded levels of carrier. (auth)
Research Organization:
New York. State Univ. Veterinary Coll., Ithaca. Lab. of Radiation Biology
NSA Number:
NSA-13-014139
OSTI ID:
4255446
Report Number(s):
AD-210708
Country of Publication:
United States
Language:
English

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Related Subjects

BIOLOGY AND MEDICINE
BODY
CALCIUM
DECONTAMINATION
DIET
DIFFUSION
EDTA
INTESTINE
IONS
LACTOSE
LIQUIDS
MEASURED VALUES
METABOLISM
QUANTITY RATIO
RADIATION DOSES
RATS
SALTS
SOLUBILITY
SOLUTIONS
STOMACH
STRONTIUM
STRONTIUM ISOTOPES
SUGARS
TRACER TECHNIQUES