THE EFFECT OF PERCHLORATE ON THE REABSORPTION OF FREE IODINE BY THE THYROID. A CONTRIBUTION TO THE ACCELERATED ELIMINATION OF INCORPORATED I-131 (in German)
Journal Article
·
· Strahlentherapie (West Germany)
OSTI ID:4229922
>Oral administration of perchlorate diminishes or blocks the reabsorption of iodine, which was liberated by the break down of thyroid hormone by the thyroid gland. After a total block of reabsorption of anorganic iodine by the thyroid gland, the thyroid becomes more and more depleted of iodine. Iodine from the food and liberated iodine from hormones is eliminated quickly by the kidneys. Therefore a prolonged administration of more than 1,200 mg perchlorate per day must be avoided. The block of iodine absorption by the thyroid gland is very useful for fast elimination of radioiodine from the thyroid gland. By this method the biological half-life of I/sup 131/ can be shortened. An increased effect can be obtained by intermittent administration of perchlorate and iodine. (auth)
- Research Organization:
- Luisenkrankenhauses, Lindenfels/Odenwald, Ger.
- NSA Number:
- NSA-13-016730
- OSTI ID:
- 4229922
- Journal Information:
- Strahlentherapie (West Germany), Journal Name: Strahlentherapie (West Germany) Vol. Vol: 109; ISSN STRAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- German
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