SPECIAL FEATURES OF THE COURSE IN INJURIES AND BURNS OF THE EYE, COMPLICATED BY RADIATION DISEASE
It was experimentally proved that healing of wounds in radiated animals is complicated by the development of a wound infection, especially during the climax period, i.e., 2 to 3 weeks after infection. This fact raised the question whether radiation disease influences also the healing process of wounds and burns ot the eye. Based on experiments on rabbits and dogs, it was concluded that the healing of ragged-penetrating injuries of the cornea without surgical treatment takes the same course in radiated rabbits as in the control rabbits and a transparent suture on injuries of the cornea of radiated rabbits, stitched after 24 hours (i.e., in the latent period of the radiation disease) helps to develop the same tight and stable scar as in control experiments. Suturation on the cornea may also be successful in patients who were exposed to ionizing radiation. Wound healing after enucleation of an eye of radiated animals did not differ much from healing of wounds in the control rabbits. The prophylaxis and treatment of purulent complications in infected wounds of the eye in radiated animals were also investigated. The data showed that the effectiveness of antibiotics is insufficient, so that the problem of tighting against infections in injuries of the eye, complicated by radiation disease, is to be considered unsolved. Experiments concerning prognosis of thermal burns of the eye in radiation disease showed that second-degree thermal burns of the cornea in radiated rabbits have the same course as those in control animals. In more serious burns, the healing is often accompanied by secondary infections in the burnt cornea, thus sharply aggravating the healing. The effects of blood transfusion as a stimulator of resoluting intraocular hemorrhage in contusions or injuries of the eye were studied. Experiments on an experimental hyphema gave evidence of the good healing effect of blood transfusions in radiation disease. Wounds of the palpebra, conjunctiva and the cornea, infected by radioactive phosphorus have a more serious course than those of noninfected wounds. It was also shown clinically and pathologically that a sharply pronounced and durable inflammation reaction and hemorrhage in tissues adjacent to the wound with following destruction and atrophy of these tissues is characteristic for infected wounds. In this case surgical treatment prevents further complications. (TCO)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-14-003451
- OSTI ID:
- 4229170
- Journal Information:
- Voenno-Med. Zhur., Journal Name: Voenno-Med. Zhur. Vol. Vol: No. 4
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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