DIPHTHERIA TOXIN OBTAINED ON MEDIA STERILIZED BY GAMMA RAYS (in Russian)
The possibility of radiation sterilization of liquid nntritive media for cultivating diphtheritic bacteria was studied. Gamma rays were employed at doses of 600,000, by irradiation does not deteriorate their nutritive properties, while the biochemical indices remain almost unchanged. The diphtheria toxin titer obtained on media sterilized by irradiation is not inferior to that derived from autoclaved media, while in a number of instances (irradiation with 600,000 r) it even surpasses it. Anatorins made of toxins from irradiated media were not inferior by their immunogenic and antigenic properties to the control preparations. These experimental data point to the possibility of cold'' sterilization of liquid nutritive media. (auth)
- Research Organization:
- Samaley Inst. of Epidemiology and Microbiology
- NSA Number:
- NSA-13-020833
- OSTI ID:
- 4222009
- Journal Information:
- Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Vol. Vol: 4, No. 8; Other Information: Orig. Receipt Date: 31-DEC-59
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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