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RADIOISOTOPES IN LIVER DIAGNOSIS (in German)

Journal Article · · Atomkernenergie (West Germany) Merged with Kerntechnik to form Atomkernenerg./Kerntech. Acta Radiol. Changed to Acta Radiol.: Oncol., Radiat. Phys.
OSTI ID:4215419
All the known diagnostic procedures in liver conditions with the help of radioisotopes are mainly based on two phenomenai radioactive substances which are excreted through the biliary system as well as isotopes which can be stored in the reticuloendothelial system of the liver may be applied. The most important publications in this field of diagnostic use of radioactive isotopes and of its results are mentioned. The purpose of the experiments which are reported here, was to glve information about the circulatory condition in various liver diseases. The method is based upon the different outflow of a radioactive substance from tissue with disturbed local circulation after intravenous application of radioactlve sodium iodide (Na/sup 131/I). Thus the local clearance'' which results from local circulation and diffusion, about which the earlier methods of determining the circulatory conditions within the liver do not give any information could be determined. After blocking the thyroid with lnactive iodine, the elimination of intravenously applicated Na/sup 131/ from the human liver was observed in vivo. The radioactivity in the normal liver disappeared rapidly (in accordance to the radioactivity in the blood); cirrhotic livers, however, showed a remarkably delayed elimination of the isotopes. A small, but noticeable difference between the elimination of isotopes from the liver in young and old sclerotic patients was also observed. (auth)
Research Organization:
Medizinschen Universitatsklinik, Cologne
NSA Number:
NSA-13-018811
OSTI ID:
4215419
Journal Information:
Atomkernenergie (West Germany) Merged with Kerntechnik to form Atomkernenerg./Kerntech. Acta Radiol. Changed to Acta Radiol.: Oncol., Radiat. Phys., Journal Name: Atomkernenergie (West Germany) Merged with Kerntechnik to form Atomkernenerg./Kerntech. Acta Radiol. Changed to Acta Radiol.: Oncol., Radiat. Phys. Vol. Vol: 4; ISSN ATKEA
Country of Publication:
Country unknown/Code not available
Language:
German

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