RNA cleavage and phosphate diester transesterification by encapsulated lanthanide ions: Traversing the lanthanide series with lanthanum(III), europium(III), and lutetium(III) complexes of 1,4,7,10-tetrakis(2-hydroxyalkyl)-1,4,7,10-tetraazacyclododecane
- State Univ. of New York, Buffalo, NY (United States)
1,4,7,10-tetrakis(2-hydroxyethyl)-1,4,7,10-tetraazacyclododecane(THED) and (1S,4S,7S,10S)-1,4,7,10-tetrakis(2hydroxypropyl)-1,4,7,10-tetraazacyclododecane (S-THP) complexes of lanthanides were evaluated with their ability to promote transesterification of the 4-nitrophenyl phosphate ester of propylene glycol (1) or the cleavage of RNA oligomers. Kinetics of the reactions were measured and rate constants are reported.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 420981
- Journal Information:
- Inorganic Chemistry, Journal Name: Inorganic Chemistry Journal Issue: 22 Vol. 33; ISSN 0020-1669; ISSN INOCAJ
- Country of Publication:
- United States
- Language:
- English
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