Synthesis of carboranylthiouracils for neutron capture therapy of malignant melanoma
- Biomedicine and Health Program, Menai (Australia)
1,2-closo-dodecaboranes synthesized from alkynyl-substituted thiouracils are potentially useful as boron neutral capture therapy agents. This work describes the synthesis, purification, and characterization of these compounds. NMR and IR spectroscopies were used to structurally characterize the products.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 420933
- Journal Information:
- Inorganic Chemistry, Journal Name: Inorganic Chemistry Journal Issue: 13 Vol. 33; ISSN 0020-1669; ISSN INOCAJ
- Country of Publication:
- United States
- Language:
- English
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