THE EFFECT OF WHOLE-BODY X-IRRADIATION ON THE LANGERHANS' ISLETS IN THE GUINEA PIG

Journal Article · Fri Jul 01 04:00:00 EDT 1960 · Radiation Research

DOI:https://doi.org/10.2307/3570871· OSTI ID:4178848

Allegretti, N; Matosic, M; Sestan, N; Slamberger, S

Sublethal total-body x irradiation of the guinea pig produces a fall in the beta / alpha -cell ratio curve of the Langerhans' islets on the second and third postirradiation days followed by an increase on the fifth day and an irregular course until day 120. By distributing the islets according to the size, it was possible to conclude that small islets showed a marked increase in the ratio immediately after x irradiation, the large ones showed an increase toward day 120, and the 5-day peak was due to the increase of the ratio in the islets of all sizes. Distribution curves made it possible to conclude that transformation of islet cells can occur. (auth)

• Research Organization: Inst. "Rudjer Boskovic," Zagreb
• Sponsoring Organization: USDOE
• NSA Number: NSA-14-017754
• OSTI ID: 4178848
• Journal Information: Radiation Research, Journal Name: Radiation Research Vol. Vol: 13
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ANIMAL CELLS
BIOLOGY AND MEDICINE
BODY
CYTOLOGY
DIAGRAMS
DISTRIBUTION
GLANDS
GUINEA PIGS
ISING MODEL
LETHAL DOSE
PANCREAS
RADIATION EFFECTS
TESTING
VOLUME
X RADIATION