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Survival of cultured mammalian cells irradiated at various depths in the LAMPF negative pion therapy beam

Technical Report ·
DOI:https://doi.org/10.2172/4173840· OSTI ID:4173840
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Cultured human kidney T-1 cells were irradiated in flasks or on coverslips at different depths in a water phantom using the Clinton P. Anderson Meson Physics Facility (LAMPF) negative pion beam. Studies of cell survival and division delay as a function of depth and recovery between doses indicate RBEs of 1.8 +- 0.3 and an ability of cells to recover between two doses of stopping pions. (auth)
Research Organization:
Los Alamos Scientific Lab., N.Mex. (USA)
DOE Contract Number:
W-7405-ENG-36
NSA Number:
NSA-33-000853
OSTI ID:
4173840
Report Number(s):
LA--6049-MS
Country of Publication:
United States
Language:
English

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Related Subjects

*L CELLS-- BIOLOGICAL RADIATION EFFECTS
*PIONS MINUS-- BIOLOGICAL RADIATION EFFECTS
560121* --Biomedical Sciences
Applied Studies--Radiation Effects--Radiation Effects on Cells--External Source
ANIMAL CELLS
BIOLOGICAL RECOVERY
CELL CULTURES
CELL DIVISION
COMPARATIVE EVALUATIONS
DEPTH DOSE DISTRIBUTIONS
FRACTIONATED IRRADIATION
MITOTIC DELAY
N48210* --Life Sciences--Radiation Effects on Cells-- External Source
PION BEAMS
RBE
SURVIVAL TIME
X RADIATION