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Title: CA-45 AND Sr-85 METABOLISM IN MAN. Progress Report for June 15, 1959- May 20, 1960

Technical Report ·
OSTI ID:4163207

Bone formation rate in a normal, healthy, young adult was observed to be 0.521 g calcium/day. Calcium balance and bone formation and destruction rates were studied in patients with disuse osetoporosis associated with quadriplegia secondary to poliomyelitis and patients with senile and posmenopausal osteoporosis. Renal strontium/calcium discrimination, studied for nine cases, was given by a mean factor of 4.3. This factor means that, exposed to trace amounts of strontium and normal calcium loads, the human kidney will produce a urine containing 4.3 atoms of strontium per unit filtered strontium for each atom calcium per unit filtered calcium. The mean value for gastrointestinal discrimination between endogenously secreted Sr/sup 85/ and Ca/sup 45/ was 1.4. The ratio of strontium-determined pool to calcium- determined pool was 1.04 plus or minus 0.13 (1 S.D.) and the corresponding ratio for bone formation values was 1.04 plus or minus 0.32 (1 S.D.) for nine patients studied. (C.J.G.)

Research Organization:
Creighton Univ., Omaha
DOE Contract Number:
AT(11-1)-587
NSA Number:
NSA-14-022715
OSTI ID:
4163207
Report Number(s):
TID-6219
Resource Relation:
Other Information: Orig. Receipt Date: 31-DEC-60
Country of Publication:
United States
Language:
English

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