SEMIANNUAL PROGRESS REPORT FOR THE PERIOD ENDING DECEMBER 31, 1959

Technical Report · Mon Oct 31 00:00:00 EST 1960

OSTI ID:4162763

A list is presented of publications and reports issued during the period. Progress is reported in the following studies: the radiation chemistry of dilute aqueous potassium oleate, ferriprotoporphyrin, ferrous Dowex-50 resin, and papain; the reaction of ferriprotoporphyrin with hydrogen peroxide: the effects of x radiation on cellular inclusions in chicken embryo livers; the effects of tritiated compounds on Escherichia coli; the late effects of wholebody x irradiation in rats following fractionation of x-ray dosage and following partial- body shielding;, the resistance to x radiation of embryonic cells of the limb buds of tadpoles; effects of x radiation upon spontaneous and evoked brain electrical activity in cats; thiamine transport across irradiated isolated rat intestine; the effect of Sr/sup 90/ beads within the rat femur; effects of irradiation on lymphocytes in freshly drawn blood; the synthesis of polyunsaturated fatty acids by fish; the isolation and cultivation of single beating heart cells from the rat heart the toxicity of hafnychloride; the effect of time between treatment and exposure and the effect of the rate of exposure on radioprotective action on mice of doses of 2-aminoisothiuronium-Br- HBr (AET) combined with 5-hydroxytryptamine creatinine sulfate (5-HT); the effects of nucleic acid preparations from leukemic mouse cells on the incidence of leukemia in mice; the demonstration of the superiority of Hippuran over Diodrast and other similar preparations as a test material for use in renograms; phantom studies on renogram techniques; the development of tracer techniques for use in clinical studies on kidney function; blood and plasma volume measurements, liver function, and hepatic blood flow; the metabolism of Sr/sup 90/ in humans; the effects of calcium on skeletal deposition of Sr/sup 85/ and Ca/sup 45/ in rats; the nature and quantitative consistency of the biological response to intravenously administered colloidal gold for the development of test procedures to estimate minimum liver blood flow and phagocytic capacity of the reticuloendothelial system; measurements of liver blcod flow using colloidal Au/ sup 198/; and the disappearance of injected phosphorus-32 labeled phosphates in the brains of mice. Studies on environmental radiation included the development of a granular collector for sampling fall-out debris from nuclear detonations; studies on the biological availability of fall-out originating from continental detonations; environmental and soil factors influencing the uptake of fission products by plants; an assessment of environmental contamination emitted by nuclear propulsion devices, and measurements of the Sr/sup 89/ and Sr/sup 90/ content of caribou and moose antlers from Alaska. Design modifications are described for several radiation detectors. Progress is reported in the development of chemical methods for the dosimetry of thermal neutrons. (For preceding period see UCLA-444.) (C.H.)

• Research Organization: California. Univ., Los Angeles. School of Medicine
• DOE Contract Number: AT-04-1-GEN-12
• NSA Number: NSA-14-013544
• OSTI ID: 4162763
• Report Number(s): UCLA-457
• Resource Relation: Other Information: Orig. Receipt Date: 31-DEC-60
• Country of Publication: United States
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
ADSORPTION- BLOOD- BLOOD CIRCULATION- BLOOD PLASMA- BONES- CALCIUM- CALCIUM 45- COLLOIDS- GOLD 198- LIVER- LYMPH SYSTEM- MAN- MEASURED VALUES- METABOLISM- RATS- RETICULOENDOTHELIAL SYSTEM- STRONTIUM 85- STRONTIUM 90- TISSUES- TOXICITY- VOLUME
AET- ANIMAL CELLS- DIODRAST- DRUGS- EFFICIENCY- HAFNIUM CHLORIDES- HEART- HIPPURAN- HIPPURIC ACID- KIDNEYS- LEUKEMIA- MEDICINE- MICE- NUCLEIC ACIDS- ORGANIC NITROGEN COMPOUNDS- ORGANIC SULFUR COMPOUNDS- PHYSIOLOGY- RADIATION EFFECTS- RADIATION PROTECTION- RADIOGRAPHY- RATS- SODIUM COMPOUNDS- TESTING- TOXICITY- TRACER TECHNIQUES
ANIMAL CELLS- ANIMALS- BIOCHE