Clinical assessment of left ventricular regional contraction patterns and ejection fraction by high-resolution gated scintigraphy

Journal Article · Wed Oct 01 04:00:00 EDT 1975 · J. Nucl. Med., v. 16, no. 10, pp. 865-874

OSTI ID:4162257

Berman, D S; Salel, A F; DeNardo, G L; Bogren, H G; Mason, D T

An improved, noninvasive, radionuclidic, gated blood-pool imaging technique was developed for clinical analysis of regional contraction abnormalities of the left ventricle and determination of ejection fraction. The principal innovations include high-resolution collimation, higher information density, improved method for dynamic aortic-mitral-diaphragmatic border delineation, accurate selection of the end-systolic gating interval through the use of the phonocardiogram, and accurate end-diastole by on-line gating immediately following the electrocardiographic QRS. The results of scintigraphic studies using /sup 99m/Tc-human serum albumin or /sup 99m/Tc-autologous erythrocytes as tracer were compared with selective radiopaque cineangiographic findings in 27 patients with cardiac disease; excellent correlations of ejection fractions and abnormal contraction patterns were demonstrated. In addition, the clinical usefulness in evaluating ventricular performance was demonstrated in 79 patients with acute and chronic coronary artery disease. (auth)

• Research Organization: Univ. of California, Davis
• NSA Number: NSA-33-001036
• OSTI ID: 4162257
• Journal Information: J. Nucl. Med., v. 16, no. 10, pp. 865-874, Journal Name: J. Nucl. Med., v. 16, no. 10, pp. 865-874; ISSN JNMEA
• Country of Publication: United States
• Language: English

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