Liver imaging in the diagnosis of hepatic venous thrombosis in paroxysmal nocturnal hemoglobinuria

Journal Article · Sat Nov 01 04:00:00 EST 1975 · Radiology, v. 117, no. 2, pp. 341-348

OSTI ID:4162076

Staab, E V; Hartman, R C; Parrott, J A

Eleven patients with paroxysmal nocturnal hemoglobinuria were studied by serial liver imaging using /sup 99m/Tc-sulfuric colloid. This disease has a generalized thrombotic tendency, and progressive diffuse hepatic venous thrombosis has been emphasized in recent studies. Radionuclide imaging proved to be of great help in establishing the diagnosis of hepatic venous thrombosis and following the progress of the disease process. Abnormal patterns in hepatic venous occlusion include enlargement of the liver (especially the right lobe), extrahepatic localization of radionuclide, and areas of decreased uptake in the distribution of the involved veins. These findings develop rapidly and are very characteristic in the clinical setting. (auth)

• Research Organization: Vanderbilt Univ., Nashville
• NSA Number: NSA-33-001072
• OSTI ID: 4162076
• Journal Information: Radiology, v. 117, no. 2, pp. 341-348, Journal Name: Radiology, v. 117, no. 2, pp. 341-348; ISSN RADLA
• Country of Publication: United States
• Language: English

Related Subjects

*HEMIC DISEASES-- DIAGNOSTIC TECHNIQUES
*LIVER-- SCINTISCANNING
*TECHNETIUM 99-- DIAGNOSTIC TECHNIQUES
*THROMBOSIS-- DIAGNOSTIC TECHNIQUES
550601* --Biomedical Sciences
Basic Studies--Medicine-- Unsealed Radionuclides in Diagnostics
ISOMERIC NUCLEI
N48830* --Life Sciences--New Tracer Techniques--Other
NUCLEAR MEDICINE
PATIENTS
RADIOCOLLOIDS
RADIONUCLIDE ADMINISTRATION
SULFUR COMPOUNDS
VEINS