SPLEEN ADENOSINE DEAMINASE AND GUANASE ACTIVITIES AFTER WHOLE-BODY X- IRRADIATION OF RATS

Journal Article · Sat Oct 01 00:00:00 EDT 1960 · Proc. Soc. Exptl. Biol. Med.

DOI:https://doi.org/10.3181/00379727-105-26024· OSTI ID:4161861

Eichel, H J

Adenoline deaminase and guanase activities were studied in homogenates and supernatant fluid fractions, respectively, prepared from spleens of control rats and animals given 600 r of whole-body x irradiation. Spectfic activities of both enzymes were increased slightly in irradiated animals but total organ activities of both enzymes were decreased as compared to levels obtained in control rats. Interpretation of these and similar findings is discussed, and it is concluded that they do not represent dangrect or indirect enzyme activation or enzyme synthesis but rather reflect loss of nitrogen content and weight, which are concomitants of splenic involution. (auth)

• Research Organization: Hahnemann Medical Coll., Philadelphia
• Sponsoring Organization: USDOE
• NSA Number: NSA-15-001293
• OSTI ID: 4161861
• Journal Information: Proc. Soc. Exptl. Biol. Med., Journal Name: Proc. Soc. Exptl. Biol. Med. Vol. Vol: 105
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
CENTRIFUGATION
ENZYMES
NITROGEN
RATS
SPLEEN
X RADIATION