THE COMPARATIVE MUTAGENIC EFFECT OF ETHYLENIMINE, ULTRAVIOLET AND X-RAYS

Journal Article · Mon Jul 11 00:00:00 EDT 1960 · Doklady Akad. Nauk S.S.S.R.

OSTI ID:4146940

Alikhanyan, S I; Zhdanova, N I

The mutagenic effects of ethylenimine were determined by the use of Actinomyces alivaceus (the product of B/sub 12/ vitamin) and compared with ultraviolet, and x ray effects. The spores were exposed to high concentrations of ethylenimine (solution of 1: 1000) for various times (30 min, 1, 2, 3, 4, and 5 hr) and to diluted concentrations (1: 3000, produced by short-time exposure to a concentrated solution; lethality at various treatments is nearly identical. The results of the comparison with ultraviolet and x rays indicate a large advantage in the use of ethylenimine. Curves of reverse mutation frequencies indicate prevailing frequencies of ethylenimine mutations over ultraviolet. This shows that regardless of genetic background changes. the advantages of ethylenimine are retained. (R.V.J.)

• Research Organization: All Union Research Inst. of Antibiotics, USSR
• NSA Number: NSA-14-023956
• OSTI ID: 4146940
• Journal Information: Doklady Akad. Nauk S.S.S.R., Vol. Vol: 133; Other Information: Orig. Receipt Date: 31-DEC-60
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

BIOLOGY AND MEDICINE
BACTERIA
BIOCHEMISTRY
BIOLOGY
CHEMICAL REACTIONS
DIAGRAMS
EFFICIENCY
ETHYLENE
GENETICS
IMINES
LETHAL DOSE
MUTATIONS
ORGANIC NITROGEN COMPOUNDS
RADIATION EFFECTS
RADIOSENSITIVITY
SENSITIVITY
SOLUTIONS
SPORES
STANDARDS
TESTING
ULTRAVIOLET RADIATION
VARIATIONS
VITAMIN B-12
VITAMINS
X RADIATION