Thymine dimer excision by extracts of human cells
Conference
·
OSTI ID:4145296
- ed.
An enzyme activity capable of excising thymine dimers in vitro from uv- irradiated, specifically incised DNA was identified in extracts of human cells. Experimental results indicate that extracts of human cells grown in tissue culture contain both uv endonuclease and dimer-excision activities. Tables are presented to show effects of uv radiation and effects of freezing cells on thymine dimer excision in cell-free extracts. (HLW)
- Research Organization:
- Stanford Univ., CA
- NSA Number:
- NSA-33-012216
- OSTI ID:
- 4145296
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
*ANIMAL CELLS-- BIOLOGICAL RADIATION EFFECTS
*DNA-- BIOLOGICAL RADIATION EFFECTS
*NUCLEASES-- CHEMICAL ANALYSIS
*THYMINE-- BIOLOGICAL RADIATION EFFECTS
560111* --Biomedical Sciences
Applied Studies--Radiation Effects--Radiation Effects on Biochemicals--In Vitro
BIOLOGICAL EFFECTS
CELL CULTURES
DIMERS
FREEZING
MAN
N48110* --Life Sciences--Radiation Effects on Biochemicals-- In-Vitro
ULTRAVIOLET RADIATION
*DNA-- BIOLOGICAL RADIATION EFFECTS
*NUCLEASES-- CHEMICAL ANALYSIS
*THYMINE-- BIOLOGICAL RADIATION EFFECTS
560111* --Biomedical Sciences
Applied Studies--Radiation Effects--Radiation Effects on Biochemicals--In Vitro
BIOLOGICAL EFFECTS
CELL CULTURES
DIMERS
FREEZING
MAN
N48110* --Life Sciences--Radiation Effects on Biochemicals-- In-Vitro
ULTRAVIOLET RADIATION