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Fast DNA sequence alignment using optical computing

Technical Report ·
DOI:https://doi.org/10.2172/414348· OSTI ID:414348
;  [1]
  1. Sandia National Labs., Albuquerque, NM (United States). Exploratory Image Processing Systems II Dept.

Alignment of DNA sequences is a necessary step prior to comparison of sequence data. High-speed alignment is needed due to the large size of DNA databases. Correlation, a standard pattern recognition technique, can be used to perform alignment. Correlation can be performed rapidly using optical techniques. Thus, optical correlation offers the potential for high-speed processing of DNA sequence data. This report describes research efforts to apply one-dimensional acousto-optical correlation methods to the problem of DNA sequence alignment. Experimental results are presented.

Research Organization:
Sandia National Labs., Albuquerque, NM (United States)
Sponsoring Organization:
USDOE, Washington, DC (United States)
DOE Contract Number:
AC04-94AL85000
OSTI ID:
414348
Report Number(s):
SAND--96-2579; ON: DE97001600
Country of Publication:
United States
Language:
English

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