Radiation-related pericarditis

Journal Article · Sat Feb 01 04:00:00 EST 1975 · Am. J. Cardiol., v. 35, no. 2, pp. 216-220

DOI:https://doi.org/10.1016/0002-9149(75)90004-1· OSTI ID:4131002

Martin, R G; Ruckdeschel, J C; Chang, P; Byhardt, R; Bouchard, R J; Wiernik, P H

To determine the incidence of pericardial effusion in patients undergoing upper mantle radiation therapy, 81 patients with Hodgkin's disease, stages I to IIIB, were selected from a protocol series of 98 patients. Twenty- four patients (29.6 percent) met X-ray criteria for the presence of pericardial effusion. Eleven of the 24 also underwent right heart catheterization to confirm the presence of pericardial effusion and to define any hemodynamic abnormality. Fourteen patients were found to have transient effusion. Five of the 11 patients have had partial pericardiectomy for symptoms and signs of cardiac tamponade. There has been no evidence of recurrent Hodgkin's disease in these surgically treated patients. Ninety-two percent of the pericardial effusions occurred in the first 12 months after the end of radiation therapy. Therapeutic implications depend on elucidation of the natural history of this process. At present close follow-up is necessary with surgical intervention for signs or symptoms of cardiac tamponade.(auth)

• Research Organization: US Public Health Service Hospital, Baltimore
• Sponsoring Organization: USDOE
• NSA Number: NSA-33-009523
• OSTI ID: 4131002
• Journal Information: Am. J. Cardiol., v. 35, no. 2, pp. 216-220, Journal Name: Am. J. Cardiol., v. 35, no. 2, pp. 216-220; ISSN AJCDA
• Country of Publication: United States
• Language: English

Related Subjects

*CARDIOVASCULAR DISEASES-- RADIOINDUCTION
*HEART-- DELAYED RADIATION EFFECTS
*RADIOTHERAPY-- SIDE EFFECTS
560151* --Biomedical Sciences
Applied Studies--Radiation Effects--Radiation Effects on Animals--Man
COBALT 60
GAMMA RADIATION
HODGKINS DISEASE
N48510* --Life Sciences--Radiation Effects on Animals--Man
PATIENTS