THE EFFECTS OF ROENTGEN WHOLE-BODY IRRADIATION ON THE ENZYMATIC ACTIVITY OF LEUCINE-AMINO-PEPTIDASE GLUTAMATE-OXALATE-AND GLUTAMATE-PYRUVATE-TRANSAMINASE IN DIFFERENT ORGANS OF MICE

Journal Article · Tue Oct 01 04:00:00 EDT 1963 · Strahlentherapie (West Germany)

OSTI ID:4127473

Braun, H; Hornung, G; Heise, E R

White mice received whole-body irradiation of 450 r. The activities of the leucine-amino-peptidase, glutamicoxalacetic-transaminase, and glutamic- pyravate-transaininase were investigated 2 to 14 days after irradiation. Twelve of 47 examined animals died at different intervals after irradiation. The irradiation caused a slight decrease of the wet weight of heant, liver, and kidney and a slight decrease of the protein content of the organ homogenates. The activity of the leucine-ainino-peptidase showed a significant decrease in all organs by the 2nd day after irradiation; the activity of the glutainic-oxalacetic- transaminase increased at the saine day in all organs; and the activity of the glutainic-pyruvate-transaininase showed at the same tiine a distinct increase only in the liver hoinogenates. A delayed increase of the pyruvate-transaminase was found in kidney homogenates. On the 14th day after irradiation an increase of leucine-amino-peptidase and glutainic-oxalacetic-transaminase was found in all organs. (auth)

• Research Organization: Universitat, Wurzburg, Ger.
• NSA Number: NSA-18-003555
• OSTI ID: 4127473
• Journal Information: Strahlentherapie (West Germany), Journal Name: Strahlentherapie (West Germany) Vol. Vol: 122; ISSN STRAA
• Country of Publication: Country unknown/Code not available
• Language: German

Related Subjects

AMINO ACIDS
BIOLOGY AND MEDICINE
BODY
DECOMPOSITION
ENZYMES
GLUTAMIC ACID
HEART
KIDNEYS
LEUCINE
LIVER
METABOLISM
MICE
ORGANIC ACIDS
PEPTIDES
PROTEINS
PYRUVIC ACID
QUANTITY RATIO
RADIATION DOSES
RADIATION EFFECTS
TRANSAMINASES
WEIGHT