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Preparation of $sup 125$I-labeled secretin of high specific radioactivity

Journal Article · · Anal. Biochem., v. 69, no. 1, pp. 34-42
OSTI ID:4119183

A simple and rapid method of preparing $sup 125$I-labeled secretin of high specific radioactivity has been developed. Synthetic porcine secretin was iodinated with Na[$sup 125$I] by a modification of the chloramine T method. Purification and separation of labeled from unlabeled secretin was achieved by chromatography on SP-Sephadex C-25 column. The labeled secretin possessed specific radioactivity as high as 500 to 550 $mu$Ci/$mu$g. (auth)

Research Organization:
Univ. of Rochester, NY
NSA Number:
NSA-33-017557
OSTI ID:
4119183
Journal Information:
Anal. Biochem., v. 69, no. 1, pp. 34-42, Journal Name: Anal. Biochem., v. 69, no. 1, pp. 34-42; ISSN ANBCA
Country of Publication:
United States
Language:
English

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