Programmed cell death for defense against anomaly and tumor formation

Journal Article · Sun Dec 31 00:00:00 EST 1995 · Transactions of the American Nuclear Society

OSTI ID:411528

Kondo, Sohei ^[1]; Norimura, Toshiyuki ^[2]; Nomura, Taisei ^[3]

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1. Kinki Univ., Higashi-Osaka (Japan)
2. Univ. of Occupational & Environmental Health, Kitakyusyu (Japan)
3. Osaka Univ., Osaka (Japan)

Cell death after exposure to low-level radiation is often considered evidence that radiation is poisonous, however small the dose. Evidence has been accumulating to support the notion that cell death after low-level exposure to radiation results from activation of suicidal genes {open_quote}programmed cell death{close_quote} or {open_quote}apoptosis{close_quote} - for the health of the whole body. This paper gives experimental evidence that embryos of fruit flies and mouse fetuses have potent defense mechanisms against teratogenic or tumorigenic injury caused by radiation and carcinogens, which function through programmed cell death.

• OSTI ID: 411528
• Report Number(s): CONF-951006-; ISSN 0003-018X; TRN: 97:000781
• Journal Information: Transactions of the American Nuclear Society, Vol. 73; Conference: Winter meeting of the American Nuclear Society (ANS), San Francisco, CA (United States), 29 Oct - 1 Nov 1995; Other Information: PBD: 1995
• Country of Publication: United States
• Language: English

Related Subjects

56 BIOLOGY AND MEDICINE
APPLIED STUDIES
FETUSES
BIOLOGICAL RADIATION EFFECTS
FRUIT FLIES
MALE GENITALS
RATS
CAFFEINE
BIOLOGICAL EFFECTS
CARCINOGENS
EMBRYOS
GENES
CELL KILLING
EXCISION REPAIR
MUTAGENESIS
NATURAL KILLER CELLS