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Reaction of DL-Threonine with Recoil Tritium Atoms

Journal Article · · Bulletin of the Chemical Society of Japan
DOI:https://doi.org/10.1246/bcsj.33.1146· OSTI ID:4110565
Investigations of the preparation of tritium-labeled organic compounds were previously carried out using recoil tritium atoms from the Li/sup 6/(n, alpha )H/sup 3/ reaction. The results are given of similar experiments using DL- threonine. In this experiment the allo-isomer was found. A mixture of DL- threonine and lithium carbonate was irradiated with thermal neutrons at a flux of 2.5 x 10/sup 11/ neutrons/cm/sup 2//sec. The irradiated mixture was dissolved in water and processed to yield 800 mg of white crystals with a specific activity of 0.113 mu c/mg. Paper chromatography of the crystals showed three spots on spraying with ninhydrine- R/sub f/ values of the spots were identical with those obtained by pure DL -threonine (0.24). allo-threonine (0.17). and glycine (0.05). respectively. (B.O.G.)
Research Organization:
Tanabe Seiyaku Co., Ltd., Osaka
Sponsoring Organization:
USDOE
NSA Number:
NSA-15-006019
OSTI ID:
4110565
Journal Information:
Bulletin of the Chemical Society of Japan, Journal Name: Bulletin of the Chemical Society of Japan Journal Issue: 8 Vol. 33; ISSN 0009-2673
Country of Publication:
Country unknown/Code not available
Language:
English

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