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Title: GAMMA IRRADIATION OF SOME UNSATURATED STEROIDS

Journal Article · · Intern. J. Appl. Radiation and Isotopes

The chemical and physical effects of radiation on some steroids, mainly in the powdered form, were investigated. The steroid hormones, cortisone, prednisone, and progesterone, were found to show high stability to radiation damage to supersterilization doses (6 to 18 Mrad) both in presence and absence of air. Ergosterol and calciferol were found to be sensitive to radioinduced oxidation in air, and their oxidation products were characterized. These reactions of ergosterol and calciferol probably proceed by a free radical chain process since the G value for product formation exceeds 20. (D.L.C.)

Research Organization:
Wantage Radiation Lab., Berks, Eng.
NSA Number:
NSA-15-008839
OSTI ID:
4103847
Journal Information:
Intern. J. Appl. Radiation and Isotopes, Vol. Vol: 9; Other Information: Orig. Receipt Date: 31-DEC-61
Country of Publication:
Country unknown/Code not available
Language:
English